Peak-Trough Screen
Understanding injected testosterone Cypionate and Enanthate's fluctuation in the body is key to understanding your treatment, becoming symptom free (dialed-in), and living your best life.
Two key things that influence testosterone's fluctuation are:
Dose: How much you take per injection (mg)
Frequency: How often you take that injection
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Together, these two factors make up your peak-trough fluctuation, however, the combination you feel best on is completely individual to you.
Our app graphs your fluctuation based off a single peak lab results. It has been designed to bridge the gap in patient-physician education and to help you find the best possible medication schedule in the shortest amount of time.
Peak-Trough Tutorial
Total Testosterone
On TRT, your testosterone level is the highest before 10am, 24-48 hours after your injection, and then falls until you take your next injection. Additionally, your testosterone levels will take up to 8 weeks to fully stabilize whenever you first start TRT, or make a change to dose or frequency, unless you were prescribed a loading dose. For the Total Testosterone box on this screen, enter the total testosterone level from a blood test that has captured your highest level of testosterone, after the medication is totally stable.
You have a choice of ng/dL or nmol/L for the units.
(unit conversion can be easily found online, if necessary)
Dose & Frequency
Dose is the amount of Testosterone Cypionate or Enanthate (mg) you have been taking for each injection, and have become fully stable on (certain steady-state).
Frequency is simply how often you take your injection. e.g., Every 7 Days, 2x Per Week, Every 3 Days, Every Day.etc.
New Dose & New Frequency
New Dose can be any amount (per injection) of Testosterone Cypionate or Enanthate (mg).
New Frequency can be any number of days for how often the New Dose is taken. e.g., Every 5 Days, Every 4 Days, EOD (Every Other Day).etc.
Results: Graph & Numbers
When Total Testosterone, Dose, and Frequency have all been entered (your current medication schedule), you will see the dark blue line come to life on the graph.
The top spike of this line (peak) is how high your total testosterone goes after your injection. The bottom spike of this line (trough) is a calculation of how low your total testosterone falls before you take your next injection. The line spikes repeat to show the ups and downs over a 24 day period but are identical, as the medication has already completely stabilized (certain steady-state).
The dark blue numbers next to the graph (left side) are your calculated high and low (peak and trough) for total testosterone based on your current dose, injection frequency, and lab result.
When a New Dose and New Frequency have been added, the light blue line will also come to life on the graph. This line, and the light blue numbers on the right side of the graph, work the exact same way as the dark blue line. The difference is the light blue information is showing your calculated high and low (peak and trough) for total testosterone based on the New Dose and New Frequency information you entered.
Special Tip: You can press and hold the graph, then drag side to side to view the in-between numbers for total testosterone. Results are color coordinated with the data you entered.
Peak-Trough Conclusion
The Peak-Trough Fluctuation screen is a powerful management tool backed by peer-reviewed pharmakokinetic equations. We designed it to help you better understand the decisions you make with your doctor, while searching for the dose and frequency combination that alleviates all of your related symptoms.
Note: An 8 day half-life has been used for the Peak-Trough Fluctuation, as is standard for Testosterone Cypionate and the median estimate for Testosterone Enanthate.
